777854

Tris(hydroxypropyl)phosphine

≥80%

• Synonym(s): THPP
• Empirical Formula (Hill Notation): C₉H₂₁O₃P
• CAS Number: 4706-17-6
• Molecular Weight: 208.24
• MDL number: MFCD00269835
• UNSPSC Code: 12352128
• PubChem Substance ID: 329767934
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: ≥80%
• form: liquid
• reaction suitability: reagent type: reductant
• density: 1.136 g/mL at 25 °C
• SMILES string: OCCCP(CCCO)CCCO
• InChI: 1S/C9H21O3P/c10-4-1-7-13(8-2-5-11)9-3-6-12/h10-12H,1-9H2
• InChI key: YICAEXQYKBMDNH-UHFFFAOYSA-N

Description

General description

Tris(hydroxypropyl)phosphine (THPP) is a reducing agent widely used for the reductive cleavage of disulfide bonds in small molecules in both aqueous–organic media.

Application

Tris(hydroxypropyl)phosphine can be used:

• As a reducing agent in the reduction of dehydroascorbic acid to ascorbic acid
• In the cleavage of disulfide bonds in small molecules
• As a catalyst in the conversion of polysulfides

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable