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MAB8599

Sigma-Aldrich

Anti-RSV Antibody, fusion protein, all type A, B strains, clone 131-2A

clone 131-2A, Chemicon®, from mouse

Synonym(s):

RSV Fusion

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Pricing and availability is not currently available.
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biological source

mouse

Quality Level

300

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

131-2A, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
flow cytometry: suitable
immunofluorescence: suitable
western blot: suitable

isotype

IgG2aκ

shipped in

wet ice

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This Item
MAB8598MAB8262XZMS1055
Anti-RSV Antibody, fusion protein, all type A, B strains, clone 131-2A clone 131-2A, Chemicon®, from mouse

MAB8599

Anti-RSV Antibody, fusion protein, all type A, B strains, clone 131-2A

Anti-RSV Antibody, fusion protein, all type A, B strains, clone 130-8F clone 130-8F, Chemicon®, from mouse

MAB8598

Anti-RSV Antibody, fusion protein, all type A, B strains, clone 130-8F

Anti-RSV Antibody, fusion protein, all type A, B strains, clone 133-1H, Alexa Fluor™ 488 clone 133/1H, Chemicon®, from mouse

MAB8262X

Anti-RSV Antibody, fusion protein, all type A, B strains, clone 133-1H, Alexa Fluor™ 488

Anti-RSV Fusion Protein Antibody, clone 131-2A ZooMAb® Mouse Monoclonal recombinant, expressed in HEK 293 cells

ZMS1055

Anti-RSV Fusion Protein Antibody, clone 131-2A ZooMAb® Mouse Monoclonal

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

virus

clone

131-2A, monoclonal

clone

130-8F, monoclonal

clone

133/1H, monoclonal

clone

131-2A, recombinant monoclonal

antibody form

purified immunoglobulin

antibody form

ascites fluid

antibody form

purified antibody

antibody form

purified antibody

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

ambient

technique(s)

ELISA: suitable, immunofluorescence: suitable, flow cytometry: suitable, western blot: suitable

technique(s)

immunofluorescence: suitable

technique(s)

immunofluorescence: suitable

technique(s)

ELISA: suitable, flow cytometry: suitable, immunocytochemistry: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, western blot: suitable

General description

RSV is a labile paramyxovirus that produces a characteristic fusion of human cells in tissue culture--the syncytial effect. Two subtypes, A and B, have been identified. Subtype B are characterized as the asymptomatic strains of the virus. The more severe clinical illnesses involve Subtype A strains.

Specificity

Reacts with RSV fusion protein, specifically epitope F1a of RSV F-protein {Sominina AA, et al Vestn Ross Akad Med Nauk. 1995;(9):49-54} found on all A & B strains of RSV.

Immunogen

A2 RSV virus cell extract
Epitope: all type A & B strains

Application

Anti-RSV Antibody, fusion protein, all type A, B strains, clone 131-2A detects level of Respiratory Syncytial Virus & has been published & validated for use in ELISA, FC, IF & WB.
Indirect immunofluorescence.

ELISA

Immunoblotting: (using purified F protein preparations, clone identified a ~70kDa band, Tripp, RA et al 2003)

Final working dilutions must be determined by end user.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral

Target description

~70 kDa

Physical form

Format: Purified
Protein A Purified immunoglobulin in 0.02M phosphate, 0.25M NaCl, 0.1% NaN3 pH 7.6
Protein A purified

Storage and Stability

Maintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Analysis Note

Control
RSV Control Slides, Catalogue Number 5012-5

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

    • Certificates of Analysis (COA)

    Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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    L M Haynes et al.
    Journal of virology, 75(22), 10730-10737 (2001-10-17)
    The mammalian Toll-like receptor 4, TLR4, is an important component in the innate immune response to gram-negative bacterial infection. The role of TLR4 in antiviral immunity has been largely unexplored. In this study, the in vivo immune responses to respiratory
    Anti-G protein antibody responses to respiratory syncytial virus infection or vaccination are associated with inhibition of G protein CX3C-CX3CR1 binding and leukocyte chemotaxis
    Harcourt, Jennifer L, et al
    The Journal of Infectious Diseases, 190, 1936-1940 (2004)
    Patricia Clua et al.
    Cells, 9(7) (2020-07-15)
    The nasal priming with nonviable Lactobacillus rhamnosus CRL1505 (NV1505) or its purified peptidoglycan (PG1505) differentially modulates the respiratory innate immune response in infant mice, improving their resistance to primary respiratory syncytial virus (RSV) infection and secondary pneumococcal pneumonia. In association
    R A Tripp et al.
    Journal of virology, 73(9), 7099-7107 (1999-08-10)
    BALB/c mice sensitized to vaccinia virus expressed G protein of respiratory syncytial virus (RSV) develop a Th2-type cytokine response and pulmonary eosinophilia when challenged with live RSV. In this study, BALB/c mice were immunized or challenged with an RSV mutant
    Subgrouping of respiratory syncytial virus strains from Australia and Papua New Guinea by biological and antigenic characteristics
    Hierholzer, J C, et al
    Archives of Virology, 136, 133-147 (1994)
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