M8277

Midodrine hydrochloride

analytical standard, for drug analysis

• Synonym(s): (±)-1-(2,5-Dimethoxyphenyl)-2-glycinamidoethanol
• Empirical Formula (Hill Notation): C₁₂H₁₈N₂O₄ · HCl
• CAS Number: 3092-17-9
• Molecular Weight: 290.74
• MDL number: MFCD00079455
• UNSPSC Code: 41116107
• PubChem Substance ID: 329818055
• NACRES: NA.24

Properties

• Quality Level: 100
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): forensics and toxicology; pharmaceutical (small molecule); veterinary
• format: neat
• SMILES string: Cl.COc1ccc(OC)c(c1)C(O)CNC(=O)CN
• InChI: 1S/C12H18N2O4.ClH/c1-17-8-3-4-11(18-2)9(5-8)10(15)7-14-12(16)6-13;/h3-5,10,15H,6-7,13H2,1-2H3,(H,14,16);1H
• InChI key: MGCQZNBCJBRZDT-UHFFFAOYSA-N
• Gene Information: human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

Description

General description

Midodrine is a prodrug and a long acting α-adrenergic stimulating agent, and forms an active metabolite, desglymidodrine, which causes an elevation of the systemic blood pressure with the reduction in heart rate.

Application

Midodrine hydrochloride may be used as an analytical reference standard for the quantification of the analyte in biological samples and pharmaceutical formulations using different chromatography techniques.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

α-Adrenergic agonist; vasoconstrictor

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H301
• Precautionary Statements: P301 + P310
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves