30408

Daidzin

≥95.0% (HPLC)

• Synonym(s): 4′,7-Dihydroxyisoflavone 7-glucoside, Daidzein 7-glucoside, Daidzein-7-O-β-D-glucopyranoside
• Empirical Formula (Hill Notation): C₂₁H₂₀O₉
• CAS Number: 552-66-9
• Molecular Weight: 416.38
• Beilstein: 59741
• MDL number: MFCD00017466
• UNSPSC Code: 41116107
• PubChem Substance ID: 57648430
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥95.0% (HPLC)
• SMILES string: OC[C@H]1O[C@@H](Oc2ccc3C(=O)C(=COc3c2)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O
• InChI: 1S/C21H20O9/c22-8-16-18(25)19(26)20(27)21(30-16)29-12-5-6-13-15(7-12)28-9-14(17(13)24)10-1-3-11(23)4-2-10/h1-7,9,16,18-23,25-27H,8H2/t16-,18-,19+,20-,21-/m1/s1
• InChI key: KYQZWONCHDNPDP-QNDFHXLGSA-N
• Gene Information: mouse ... Aldh1a2(19378), Maoa(17161) ; rat ... Aldh1a2(116676)

Description

Biochem/physiol Actions

Daidzin is an isoflavone reported to have anti-oxidant, anti-carcinogenic, and anti-artherosclerotic activities. Daidzin is the major active component of the traditional Chinese medicine (TCM) derived from radix puerariae (Kudzu) that is commonly used to treat alcohol abuse. Daidzin is a potent and selective inhibitor of mitochondrial aldehyde dehydrogenase 2 (ALDH-2).

Daidzin was the most potent isoflavone glycoside tested in modulating differentiation of bone marrow stromal cells toward osteoblasts and away from adipocytes.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves