90190

Transferrin from human blood plasma

≥95% (GE)

• Synonym(s): Human transferrin, Siderophilin
• CAS Number: 11096-37-0
• EC Number: 234-318-8
• MDL number: MFCD00132442
• UNSPSC Code: 12352202
• NACRES: NA.61

Properties

• biological source: human plasma
• Assay: ≥95% (GE)
• form: powder or crystals
• mol wt: M_r ~79550
• technique(s): tissue culture: suitable
• impurities: ≤0.01% iron traces (AAS)
• solubility: H₂O: 50 mg/mL, clear, colorless to faintly yellow or pink
• UniProt accession no.: P02787
• storage temp.: 2-8°C
• Gene Information: human ... TF(7018)

Description

Application

Transferrin is an important supplement in serum-free tissue culture media.

Biochem/physiol Actions

Transferrin is glycoprotein, approx. 80 kDa, with two binding sites for iron. It transports iron from its primary store in the liver to tissues that require iron, primarily bone marrow and spleen, but also brain. It binds Fe³⁺ extremely tightly (Kdiss 10^-30 to 10^-27), protecting against oxidant effects of free plasma iron.

Other Notes

Review: Iron transport and storage

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable