C2624

Carbonic Anhydrase from bovine erythrocytes

≥95% (SDS-PAGE), specific activity ≥3,500 W-A units/mg protein, lyophilized powder

• Synonym(s): Carbonic Anhydrase from bovine erythrocytes, Carbonate Dehydratase, Carbonate Hydrolyase
• CAS Number: 9001-03-0
• EC Number: 4.2.1.1 (BRENDA, IUBMB)
• EC Number: 232-576-6
• MDL number: MFCD00081467
• UNSPSC Code: 12352204
• NACRES: NA.54

Properties

• biological source: bovine erythrocytes
• Assay: ≥75% protein basis (biuret); ≥95% (SDS-PAGE)
• form: lyophilized powder
• specific activity: ≥3,500 W-A units/mg protein
• solubility: deionized water: >10 mg/mL
• storage temp.: 2-8°C

Description

Application

Carbonic anhydrase, from bovine erythrocytes, is used to create carbon dioxide capture systems and to research various purification techniques . Carbonic anhydrase is also used to study acid-base regulation in fish and carbonic anhydrase type II deficiency syndrome .

Biochem/physiol Actions

Carbonic Anhydrase is a zinc-containing enzyme that catalyzes the reversible conversion of carbon dioxide to bicarbonate. One of its main physiological roles is to maintain the acid-base balance in blood and other tissues. Lack of carbonic anhydrase results in carbonic anhydrase type II deficiency syndrome, which is an autosomal recessive disease that causes osteopetrosis, renal tubular acidosis and brain calcifications .

Unit Definition

One Wilbur-Anderson (W-A) unit will cause the pH of a 0.02 M Trizma buffer to drop from 8.3 to 6.3 per min at 0°C. (One W-A unit is essentially equivalent to one Roughton-Booth unit.)

Safety Information

• Pictograms: GHS08
• Signal Word: Danger
• Hazard Statements: H334
• Precautionary Statements: P261 - P284 - P501
• Hazard Classifications: Resp. Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable