D8015

4-Dimethylaminoantipyrine

reactive nitrogen species scavenger

• Synonym(s): 4-Dimethylamino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one, Aminopyrine
• Empirical Formula (Hill Notation): C₁₃H₁₇N₃O
• CAS Number: 58-15-1
• Molecular Weight: 231.29
• EC Number: 200-365-8
• MDL number: MFCD00003142
• UNSPSC Code: 12352116
• PubChem Substance ID: 24894178
• NACRES: NA.77

Properties

• Quality Level: 200
• form: solid
• mp: 107-109 °C (lit.)
• SMILES string: CN(C)C1=C(C)N(C)N(c2ccccc2)C1=O
• InChI: 1S/C13H17N3O/c1-10-12(14(2)3)13(17)16(15(10)4)11-8-6-5-7-9-11/h5-9H,1-4H3
• InChI key: RMMXTBMQSGEXHJ-UHFFFAOYSA-N

Description

Application

Oxidation by Fe(VI) has potential to remove N-nitrosodiumethylamine precursors, including 4-dimethylaminoantipyrine, from drinking water. 4-Dimethylaminoantipyrine is itself an effective scavenger of reactive nitrogen compounds nitric oxide and peroxynitrite, important in the inflammatory response.

Biochem/physiol Actions

Antipyrine was found to be nonmutagenic when screened against Salmonella typhimurium tester strains TA100, TA98, TA97, TA102 and TA104.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H301,H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves