D8388

Dimethyl pimelimidate dihydrochloride

powder

• Synonym(s): DMP, Dimethyl pimelinediimidate dihydrochloride
• Linear Formula: [CH₃OC(=NH)CH₂CH₂]₂CH₂ · 2HCl
• CAS Number: 58537-94-3
• Molecular Weight: 259.17
• EC Number: 261-320-6
• MDL number: MFCD00038942
• UNSPSC Code: 12171500
• PubChem Substance ID: 24894208
• NACRES: NA.25

Properties

• form: powder
• Quality Level: 200
• reaction suitability: reagent type: cross-linking reagent
• solubility: H₂O: 10 mg/mL
• storage temp.: −20°C
• SMILES string: Cl.Cl.COC(=N)CCCCCC(=N)OC
• InChI: 1S/C9H18N2O2.2ClH/c1-12-8(10)6-4-3-5-7-9(11)13-2;;/h10-11H,3-7H2,1-2H3;2*1H
• InChI key: LRHXBHUTQWIZTN-UHFFFAOYSA-N

Description

General description

Dimethyl pimelimidate dihydrochloride is a homobifunctional cross-linking reagent used in crosslinking, protein interaction and protein modification. It typically reacts with primary amines in the pH range 7.0-10.0 to form amidine bonds.

Application

Dimethyl pimelimidate dihydrochloride has been used to develop a technique for isolating Enterocytozoon bieneusi spores directly from human stool samples with a high degree of purity, which opens up new approaches for studying this parasite.

Caution

The reagent is readily hydrolyzed at neutral pH.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Note that the amidine linkage preserves original primary amine positive charge. Incorporates a seven atom linker.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315
• Precautionary Statements: P264 - P280 - P302 + P352 - P332 + P313 - P362 + P364
• Hazard Classifications: Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves