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Key Documents

H7283

Sigma-Aldrich

Heat Shock Protein 70 human

recombinant, expressed in E. coli, buffered aqueous solution, ≥90% (SDS-PAGE)

Synonym(s):

HSP 70

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.32

biological source

human

Quality Level

recombinant

expressed in E. coli

Assay

≥90% (SDS-PAGE)

form

buffered aqueous solution

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... HSPA8(3312)

Application

Heat shock protein 70 human has been used as a control for checking antibody reactivity.

Biochem/physiol Actions

HSPA8 (heat shock 70kDa protein 8) is a human cytoplasmic chaperone which is involved in protein folding, protein aggregation prevention and protein transport. During nutrient stress, it participates in antigen transport to regulate MHC (major histocompatibility) class II presentation. It is upregulated in cancer cells and is involved in protein homeostasis, leading to cancer cell growth and survival.

Physical form

Solution in 2.7 mM KCl, 1.5 mM KH2PO4, 137 mM NaCl, and 8.1 mM Na2HPO4.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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