I2764

ML-7

powder

• Synonym(s): 1-(5-Iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride
• Empirical Formula (Hill Notation): C₁₅H₁₇IN₂O₂S · HCl
• CAS Number: 110448-33-4
• Molecular Weight: 452.74
• MDL number: MFCD00065524
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278490
• NACRES: NA.77

Properties

• Assay: ≥98% (TLC)
• Quality Level: 200
• form: powder
• color: white
• solubility: ethanol: water (1:1): 10 mg/mL, clear, colorless to faintly yellow
• storage temp.: −20°C
• SMILES string: Cl.Ic1cccc2c(cccc12)S(=O)(=O)N3CCCNCC3
• InChI: 1S/C15H17IN2O2S.ClH/c16-14-6-1-5-13-12(14)4-2-7-15(13)21(19,20)18-10-3-8-17-9-11-18;/h1-2,4-7,17H,3,8-11H2;1H
• InChI key: KDDALCDYHZIZMH-UHFFFAOYSA-N
• Gene Information: human ... MYLK(4638), MYLK2(85366)

Description

Application

ML-7 has been used as a myosin light chain kinase (MLCK) inhibitor in various experiments.

Biochem/physiol Actions

Selective myosin light chain kinase inhibitor.

Features and Benefits

This compound is featured on the Ca/CaMKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves