M3778

N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride

≥97% (GC)

• Synonym(s): Clorgyline
• Empirical Formula (Hill Notation): C₁₃H₁₅Cl₂NO · HCl
• CAS Number: 17780-75-5
• Molecular Weight: 308.63
• EC Number: 241-760-5
• MDL number: MFCD00052012
• UNSPSC Code: 12352116
• PubChem Substance ID: 24278179
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥97% (GC)
• form: powder
• solubility: DMSO: 10 mg/mL, clear, colorless to faintly yellow
• storage temp.: 2-8°C
• SMILES string: Cl.CN(CCCOc1ccc(Cl)cc1Cl)CC#C
• InChI: 1S/C13H15Cl2NO.ClH/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15;/h1,5-6,10H,4,7-9H2,2H3;1H
• InChI key: BBAZDLONIUABKI-UHFFFAOYSA-N
• Gene Information: human ... MAOA(4128) ; rat ... Maoa(29253), Maob(25750)

Description

Application

N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride has been used as a monoamine oxidase A (MAO-A) inhibitor:

• in MAO-A biochemical assay
• to study its effects on the transit of serotonin (5-HT) in the human placenta explants
• to study its effects on human prostate cancer cells

Biochem/physiol Actions

MAO-A inhibitor.

Features and Benefits

This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H301,H312 + H332
• Precautionary Statements: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves