N3014

β-Nicotinamide adenine dinucleotide hydrate

suitable for cell culture, ≥96.5% (HPLC), ≥96.5% (spectrophotometric assay), from yeast

• Synonym(s): β-DPN, β-NAD, Coenzyme 1, Cozymase, DPN, Diphosphopyridine nucleotide, NAD, Nadide
• Empirical Formula (Hill Notation): C₂₁H₂₇N₇O₁₄P₂ · xH₂O
• CAS Number: 53-84-9
• Molecular Weight: 663.43 (anhydrous basis)
• MDL number: MFCD00036253
• UNSPSC Code: 41106305
• eCl@ss: 39200202
• PubChem Substance ID: 24897613
• NACRES: NA.55

Properties

• biological source: yeast
• Quality Level: 200
• Assay: ≥96.5% (HPLC); ≥96.5% (spectrophotometric assay)
• form: powder
• mol wt: M_w 663.43 g/mol
• technique(s): cell culture | mammalian: suitable
• impurities: ≤3% Acetone
• color: white to off-white
• solubility: H₂O: 50 mg/mL
• storage temp.: −20°C
• SMILES string: NC1=NC=NC2=C1N=CN2.O[C@@H]3[C@@H](COP(O)(OP(OC[C@@H](O4)[C@@H](O)[C@@H](O)[C@H]4[N+]5=CC=CC(C(N)=O)=C5)([O-])=O)=O)OC[C@@H]3O
• InChI: 1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
• InChI key: BAWFJGJZGIEFAR-NNYOXOHSSA-N
• Gene Information: human ... ESR1(2099), ESR2(2100)

Description

Application

• Spectroelectrochemical Enzyme Sensor System for Acetaldehyde Detection in Wine.: This study explores the development of a novel sensor system using β-Nicotinamide adenine dinucleotide hydrate to detect acetaldehyde in wine, enhancing the accuracy of wine quality control (Ibáñez et al., 2022).


• Screening of Lactate Dehydrogenase Inhibitor from Bioactive Compounds in Natural Products by Electrophoretically Mediated Microanalysis.: The research utilizes β-Nicotinamide adenine dinucleotide hydrate to screen potential lactate dehydrogenase inhibitors, which could lead to new therapeutic agents for diseases such as cancer (Li et al., 2021).


• Combination of NAD(+) and NADPH Offers Greater Neuroprotection in Ischemic Stroke Models by Relieving Metabolic Stress.: This research highlights the neuroprotective effects of NAD+ and NADPH in stroke models, emphasizing the potential therapeutic applications of β-Nicotinamide adenine dinucleotide hydrate in neuroprotection (Huang et al., 2018).

Biochem/physiol Actions

Electron acceptor

Packaging

Packaged by solid weight.

Other Notes

Meets or exceeds NRC specifications.

This is the common form of NAD.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable