N7627

L-Norvaline

≥99% (TLC)

• Synonym(s): (S)-(+)-2-Aminopentanoic acid, (S)-2-Aminovaleric acid
• Linear Formula: CH₃CH₂CH₂CH(NH₂)CO₂H
• CAS Number: 6600-40-4
• Molecular Weight: 117.15
• Beilstein: 1721162
• EC Number: 229-543-3
• MDL number: MFCD00064421
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24897833
• NACRES: NA.26

Properties

• Product Name: L-Norvaline, arginase inhibitor
• Quality Level: 200
• Assay: ≥99% (TLC)
• form: powder
• color: white
• mp: >300 °C (lit.)
• application(s): detection
• SMILES string: CCC[C@H](N)C(O)=O
• InChI: 1S/C5H11NO2/c1-2-3-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
• InChI key: SNDPXSYFESPGGJ-BYPYZUCNSA-N

Description

Application

• Nanodrugs mediate TAMs-related arginine metabolism interference to boost photodynamic immunotherapy.: This study explores the use of nanodrugs to interfere with arginine metabolism in tumor-associated macrophages (TAMs), enhancing the efficacy of photodynamic immunotherapy. L-Norvaline plays a crucial role in this metabolic interference (Chen et al., 2024).

Biochem/physiol Actions

L-Norvaline enhances NO production from activated macrophages.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves