SML3662

Etrasimod arginine

≥98% (HPLC)

• Synonym(s): APD 334 L-Arginine, L-Arginine mono[(3R)-7-[[4-cyclopentyl-3-(trifluoromethyl)phenyl]methoxy]-1,2,3,4-tetrahydrocyclopent[b]indol-3-yl]acetate, L-Arginine salt of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid
• Empirical Formula (Hill Notation): C₃₂H₄₀F₃N₅O₅
• CAS Number: 1206123-97-8
• Molecular Weight: 631.69
• UNSPSC Code: 12352209
• UNSPSC Code: 12352200
• NACRES: NA.25

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear (Warmed)
• storage temp.: -10 to -25°C
• SMILES string: N[C@@H](CCCNC(N)=N)C(O)=O.O=C(O)C[C@H]1CCC2=C1NC3=C2C=C(OCC4=CC=C(C5CCCC5)C(C(F)(F)F)=C4)C=C3
• InChI key: GVPVVOSNDUAUKM-BPGOJFKZSA-N

Description

Biochem/physiol Actions

Etrasimod arginine is an orally available, potent, and selective agonist of Sphingosine-1-Phosphate Receptors 1 (S1PR1). Also, it acts as a partial agonist of S1PR4,5. Etrasimod arginine induces reductions in lymphocyte counts in mice. It is acting as immunosuppressive agents.

Orally available, potent, and selective agonist of Sphingosine-1-Phosphate Receptors 1 (S1PR1)

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable