168734
4,4′-Dihydroxybiphenyl
97%
Synonym(s):
4,4′-Biphenol, 4,4′-Biphenyldiol, 4,4′-Diphenol
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About This Item
Linear Formula:
HOC6H4C6H4OH
CAS Number:
Molecular Weight:
186.21
Beilstein:
1908886
EC Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23
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Quality Level
Assay
97%
form
powder
mp
280-282 °C (lit.)
SMILES string
Oc1ccc(cc1)-c2ccc(O)cc2
InChI
1S/C12H10O2/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10/h1-8,13-14H
InChI key
VCCBEIPGXKNHFW-UHFFFAOYSA-N
Gene Information
human ... ESR1(2099), ESR2(2100), MMP3(4314)
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Related Categories
Application
Used in the preparation of polyether liquid crystals.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 3 - Self-heat. 2 - Skin Sens. 1
Storage Class Code
4.2 - Pyrophoric and self-heating hazardous materials
WGK
WGK 2
Flash Point(F)
537.8 °F
Flash Point(C)
281 °C
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Angewandte Chemie (International Edition in English), 106, 1563-1563 (1994)
Rainer-B Volk et al.
Microbiological research, 161(2), 180-186 (2006-01-24)
The antimicrobial activity of two cyanobacterial exometabolites, norharmane (9H-pyrido(3,4-b)indole) and 4,4'-dihydroxybiphenyl, was determined in suspension assays. Good anticyanobacterial activities (concentrations of 8-80 microg ml(-1)) and moderate antibacterial (16-160 microg ml(-1)) and antifungal (32-40 microg ml(-1)) activities were found for both
You Jung Kim et al.
Biological & pharmaceutical bulletin, 28(2), 323-327 (2005-02-03)
The color of mammalian skin is determined by many factors, for which visible ones are the degree and distribution of melanin pigmentation. Because tyrosinase, (polyphenol oxidase) is the key enzyme for melanin biosynthesis, the use of various tyrosinase inhibitors is
J H Golbeck et al.
Journal of bacteriology, 156(1), 49-57 (1983-10-01)
Biphenyl metabolism in Aspergillus toxicarius occurs by successive hydroxylations in the 4- and 4'-positions, followed by conjugation with sulfate to produce 4-hydroxybiphenyl-O-sulfonic acid and 4,4'-dihydroxybiphenyl-O-sulfonic acid. The hydroxylation reactions normally occur only after a prolonged lag period after which the
Jae Kyung No et al.
Biological & pharmaceutical bulletin, 29(1), 14-16 (2006-01-06)
In our previous study, we showed that 4,4'-dihydroxybiphenyl (44'-BP) reduced melanin content via the inhibition of tyrosinase. In the current study, we utilized 44'-BP treated B16 melanoma cells (B16 cells) to measure several key cellular parameters known to be involved
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