112208

4-Nitrobenzoyl chloride

98%

• 동의어(들): p-Nitrobenzoyl chloride
• Linear Formula: O₂NC₆H₄COCl
• CAS Number: 122-04-3
• Molecular Weight: 185.56
• Beilstein: 473192
• EC Number: 204-517-4
• MDL number: MFCD00007345
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24847076
• NACRES: NA.22

속성

• Quality Level: 200
• 분석: 98%
• 양식: solid
• bp: 202-205 °C/105 mmHg (lit.)
• mp: 71-74 °C (lit.)
• 작용기: acyl chloride; nitro
• SMILES string: [O-][N+](=O)c1ccc(cc1)C(Cl)=O
• InChI: 1S/C7H4ClNO3/c8-7(10)5-1-3-6(4-2-5)9(11)12/h1-4H
• InChI key: SKDHHIUENRGTHK-UHFFFAOYSA-N

설명

일반 설명

4-Nitrobenzoyl chloride reacts with triphenylphosphonium salt to synthesize benzofurans (potential positron emission tomography (PET) tracers) by the intramolecular Wittig reaction.It has been used for the derivatisation of Adiol (Androstenediol, an endogenous proliferation agent of prostate cancer).

애플리케이션

<ul>
<li><strong>Automated Synthesis of [11C]PiB:</strong> 4-Nitrobenzoyl chloride is utilized in the automated synthesis of [11C]PiB, a radiopharmaceutical for PET imaging of amyloid, highlighting its role in enhancing neuroimaging techniques (Singh et al., 2024).</li>
</ul>

안전성 정보

• 픽토그램: GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H290,H314
• 예방조치 성명서: P234 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 1
• Flash Point (°F): 215.6 °F - closed cup
• Flash Point (°C): 102 °C - closed cup
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges