143502

Trimethylacetic anhydride

99%

• 동의어(들): Pivalic anhydride, 2,2-Dimethylpropionic anhydride
• Linear Formula: [(CH₃)₃CCO]₂O
• CAS Number: 1538-75-6
• Molecular Weight: 186.25
• Beilstein: 386552
• EC Number: 216-263-1
• MDL number: MFCD00008842
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24848589
• NACRES: NA.22

속성

• Quality Level: 200
• 분석: 99%
• 양식: liquid
• refractive index: n20/D 1.409 (lit.)
• bp: 193 °C (lit.)
• density: 0.918 g/mL at 25 °C (lit.)
• 작용기: anhydride; ester
• SMILES string: CC(C)(C)C(=O)OC(=O)C(C)(C)C
• InChI: 1S/C10H18O3/c1-9(2,3)7(11)13-8(12)10(4,5)6/h1-6H3
• InChI key: PGZVFRAEAAXREB-UHFFFAOYSA-N

설명

애플리케이션

Acylation and esterification reagent for anilines and phenols, respectively.

Trimethylacetic anhydride was used:

• in solid-phase oligonucleotide synthesis
• in kinetic resolution of racemic 2-hydroxy-γ-butyrolactones with diphenylacetic acid
• as acylation and esterification reagent for anilines
• as acylation and esterification reagent for phenols

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302,H315,H317,H319,H335
• 예방조치 성명서: P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): 162.5 °F - closed cup
• Flash Point (°C): 72.5 °C - closed cup
• 개인 보호 장비: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter