15149

N,N-Bis(phosphonomethyl)glycine

≥98.0% (T)

• 동의어(들): N-(Carboxymethyl)iminodi(methylphosphinic acid), Glyphosine
• 실험식(Hill 표기법): C₄H₁₁NO₈P₂
• CAS Number: 2439-99-8
• Molecular Weight: 263.08
• Beilstein: 1884944
• EC Number: 219-468-4
• MDL number: MFCD00056670
• UNSPSC 코드: 12352100
• PubChem Substance ID: 329750747
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: ≥98.0% (T)
• 작용기: amine; carboxylic acid
• SMILES string: O=P(CN(CP(O)(O)=O)CC(O)=O)(O)O
• InChI: 1S/C4H11NO8P2/c6-4(7)1-5(2-14(8,9)10)3-15(11,12)13/h1-3H2,(H,6,7)(H2,8,9,10)(H2,11,12,13)
• InChI key: OXHDYFKENBXUEM-UHFFFAOYSA-N

설명

일반 설명

N,N-Bis(phosphonomethyl)glycine was present in the ligand bound to human apotransferrin.

애플리케이션

Application: Complexing agent; pK-values: pK1: ·2, pK2: 2.0, pK3: 5.20, pK4: 6.77, pK5: 10.89

Anti-diabetic; delay onset of diabetes in non-obese NOD mice

Glyphosine binds to a pocket of MHC class II molecules I-Ag7 and DQ8, and modify T cell responses to the autoantigenic insulin B chain fragment 9–23 (B:9–23) peptide. Glyphosine stimulate IL-10 production and delay onset of diabetes in non-obese NOD mice.†

생화학적/생리학적 작용

Anti-diabetic; delay onset of diabetes in non-obese NOD mice

안전성 정보

• 픽토그램: GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H318
• 예방조치 성명서: P280 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves