363839

N-(tert-Butoxycarbonyl)-p-toluenesulfonamide

• Linear Formula: CH₃C₆H₄SO₂NHCO₂C(CH₃)₃
• CAS Number: 18303-04-3
• Molecular Weight: 271.33
• MDL number: MFCD00134267
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24862365
• NACRES: NA.22

속성

• mp: 121-123 °C (lit.)
• solubility: chloroform: soluble 25 mg/mL, clear, colorless
• 작용기: amine
• SMILES string: Cc1ccc(cc1)S(=O)(=O)NC(=O)OC(C)(C)C
• InChI: 1S/C12H17NO4S/c1-9-5-7-10(8-6-9)18(15,16)13-11(14)17-12(2,3)4/h5-8H,1-4H3,(H,13,14)
• InChI key: DUTLOVSBVBGNDM-UHFFFAOYSA-N

설명

일반 설명

N-(tert-Butoxycarbonyl)-p-toluenesulfonamide is a N-substituted sulphonamide and its reaction with N-trityl L-serine esters under Mitsunobu reaction conditions is reported. It can be directly coupled with primary, secondary and allylic alcohols under Mitsunobu conditions to afford various sulfonyl-protected amines.

애플리케이션

N-(tert-Butoxycarbonyl)-p-toluenesulfonamide may be used in the preparation of enyne amide, precursor for Pauson-Khand reaction.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable