595314

1-Methylpyrazole-4-boronic acid pinacol ester

95%

• 동의어(들): 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole, 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole, 1-Methyl-4-pyrazoleboronic acid pinacol ester, 2-(1-Methylpyrazol-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-methylpyrazole
• 실험식(Hill 표기법): C₁₀H₁₇BN₂O₂
• CAS Number: 761446-44-0
• Molecular Weight: 208.07
• MDL number: MFCD03789259
• UNSPSC 코드: 12352103
• PubChem Substance ID: 24881568
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: 95%
• 양식: solid
• mp: 59-64 °C (lit.)
• SMILES string: Cn1cc(cn1)B2OC(C)(C)C(C)(C)O2
• InChI: 1S/C10H17BN2O2/c1-9(2)10(3,4)15-11(14-9)8-6-12-13(5)7-8/h6-7H,1-5H3
• InChI key: UCNGGGYMLHAMJG-UHFFFAOYSA-N

설명

애플리케이션

Reagent used for

• Suzuki-Miyaura cross-coupling reactions
• Transesterification reactions

Reagent used for preparation of

• Aminothiazoles as γ-secretase modulators
• Amino-pyrido-indol-carboxamides, as potential JAK2 inhibitors for myeloproliferative disorders therapy
• Pyridine derivatives as TGF-β1 and activin A signalling inhibitors
• MK-2461 analogs as inhibitors of c-Met kinase for the treatment of cancer

Stable alternative to the boronic acid for Suzuki-Miyaura palladium-catalyzed cross-coupling

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Faceshields, Gloves