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Merck
모든 사진(1)

주요 문서

913057

Sigma-Aldrich

Alginate methacrylate

medium viscosity, average degree of methacrylation 25%

동의어(들):

AlMA, AlginateMA, Alginte, Methacrylate-modified alginate, Methacrylated alginate

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About This Item

Linear Formula:
(C13H17O10Na)m(C6H7O7Na)n
UNSPSC 코드:
12352201
NACRES:
NA.23

Quality Level

양식

(Powder or chunk(s) or fibers)

색상

light yellow

적합성

conforms to structure for NMR

저장 온도

−20°C

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애플리케이션

Alginate is an anionic polysaccharide that is widely used in pharmaceutical and biomedical applications due to its non-animal origin, low toxicity, biocompatibility, and biodegradability. Alginate hydrogels are commonly used to fabricate tissue engineering scaffolds, bioinks for 3D bioprinting, and nanocarriers for drug & gene delivery. While alginate is commonly crosslinked into a hydrogel via ionic-crosslinking with divalent cations (e.g., Ca2+), these gels feature limited long-term stability due to exchange reactions and migration of divalent cations from the alginate matrix. To prevent matrix degradation, alginate can be functionalized with reactive groups that can be chemically crosslinked, such as methacrylates. Methacrylate-functionalized alginate can be used to prepare hydrogels by thermal or photochemical crosslinking of the terminal methacrylates. Properties of the resulting hydrogel (e.g., stiffness, swelling ratio, rate of degradation) can be tuned by alginate molecular weight, degree of methacrylate functionalization, and crosslink density.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

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