924229

(S,R,S)-AHPC-Me

95%

• 동의어(들): (2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide, PROTAC^® research ligand, VH032 methyl derivative
• 실험식(Hill 표기법): C₂₃H₃₂N₄O₃S
• CAS Number: 1948273-02-6
• Molecular Weight: 444.59
• MDL number: MFCD31630815
• UNSPSC 코드: 12352101
• NACRES: NA.22

속성

• ligand: VH032
• Quality Level: 100
• 분석: 95%
• 양식: powder
• 저장 온도: 2-8°C
• SMILES string: C([C@H](C(C)(C)C)N)(=O)N1[C@H](C(N[C@@H](C)C2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1
• InChI: 1S/C23H32N4O3S/c1-13(15-6-8-16(9-7-15)19-14(2)25-12-31-19)26-21(29)18-10-17(28)11-27(18)22(30)20(24)23(3,4)5/h6-9,12-13,17-18,20,28H,10-11,24H2,1-5H3,(H,26,29)/t13-,17+,18-,20+/m0/s1
• InChI key: JOSFQWNOUSNZBP-UUZHKXTQSA-N

설명

애플리케이션

(S,R,S)-AHPC-Me is a VH032 derivative used in the recruitment of the von Hippel-Lindau (VHL) protein for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This was previously listed under ATEH961B8E6E.

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기타 정보

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법적 정보

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable