857371P

VU0359595

(1R,2R)-N-([S]-1-{4-[5-bromo-2-oxo-2,3-dihydro-1H-benzo(d)imidazol-1-yl]piperidin-1-yl}propan-2-yl)-2-phenylcyclopropanecarboxamide, powder

• 동의어(들): EVJ; VU0359595
• 실험식(Hill 표기법): C₂₅H₂₉BrN₄O₂
• CAS Number: 1246303-14-9
• Molecular Weight: 497.43
• MDL number: MFCD22416858
• UNSPSC 코드: 12352211
• NACRES: NA.25

속성

• 분석: >99% (TLC)
• 양식: powder
• 포장: pkg of 1 × 1 mg (857371P-1mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand 857371P
• 지질 유형: bioactive lipids
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: Brc1cc2[nH][c]([n](c2cc1)C3CCN(CC3)C[C@@H](NC(=O)[C@H]4[C@@H](C4)c5ccccc5)C)=O
• InChI key: JSVNNLRZCJAYTQ-ORYQWCPZSA-N

설명

일반 설명

VU0359595 has been shown to selectively inhibit the PLD1 isoform at nM levels (see data below). **Images added as .gif in folder

애플리케이션

VU0359595 has been used as PLD2 (phospholipase D2) inhibitor to quantitatively address functional and molecular aspects of the involvement of PLD-derived phosphatidic acid (PA) in regulated exocytosis and as PLD1 inhibitor to treat the knockout mice to study its effects on them.

생화학적/생리학적 작용

VU0359595 helps to block phospholipase D (PLD) which in turn reduces deoxyribonucleoside triphosphate (dNTP) biosynthesis in glioma models.

포장

5 mL Amber Glass Screw Cap Vial (857371P-1mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable