857372P

VU0285655-1

N-{2-[4-oxo-1-phenyl-1,3,8-triazaspiro(4.5)decan-8-yl]ethyl}quinoline-3-carboxamide, powder

• 동의어(들): APV; VU0285655-1
• 실험식(Hill 표기법): C₂₅H₂₇N₅O₂
• CAS Number: 1158347-73-9
• Molecular Weight: 429.51
• MDL number: MFCD22416859
• UNSPSC 코드: 12352211
• NACRES: NA.25

속성

• 분석: >99% (TLC)
• 양식: powder
• 포장: pkg of 1 × 1 mg (857372P-1mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand 857372P
• 지질 유형: bioactive lipids
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: O=C(C1=CN=C(C=CC=C2)C2=C1)NCCN(CC3)CCC43N(C5=CC=CC=C5)CNC4=O
• InChI: 1S/C25H27N5O2/c31-23(20-16-19-6-4-5-9-22(19)27-17-20)26-12-15-29-13-10-25(11-14-29)24(32)28-18-30(25)21-7-2-1-3-8-21/h1-9,16-17H,10-15,18H2,(H,26,31)(H,28,32)
• InChI key: WJOCDBUFEUKYNI-UHFFFAOYSA-N

설명

애플리케이션

VU0285655-1 has been used to study its role in membrane type 1 matrix metalloproteinase (MT1-MMP) surface trafficking and lung metastasis of mouse breast cancer cells. It has also been used as a phospholipase D-2 (PLD2) inhibitor to study its role in regulated exocytosis.

생화학적/생리학적 작용

VU0285655-1 or N-2-[4-oxo-1-phenyl-1,3,8-triazaspiro(4,5)decan-8-yl]ethyl quinoline-3-carboxamide is a phospholipase D-2 (PLD2) inhibitor. It promotes autophagy in colorectal cancer cells.

포장

5 mL Amber Glass Screw Cap Vial (857372P-1mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3