860462P

N-C16-deoxysphinganine

N-palmitoyl-1-deoxysphinganine (m18:0/16:0), powder

• 동의어(들): N-hexadecanoyl-1-deoxysphinganine (m18:0/16:0); N-C16-1-deoxyDHCer; 110960
• 실험식(Hill 표기법): C₃₄H₆₉NO₂
• CAS Number: 378755-69-2
• Molecular Weight: 523.92
• MDL number: MFCD00152125
• UNSPSC 코드: 12352211
• NACRES: NA.25

속성

• 분석: >99% (TLC)
• 양식: powder
• 포장: pkg of 1 × 1 mg (860462P-1mg); pkg of 1 × 5 mg (860462P-5mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand 860462P
• 지질 유형: sphingolipids; bioactive lipids
• 배송 상태: dry ice
• 저장 온도: −20°C

설명

일반 설명

Commonly referred to as 1-deoxydihydroceramide (1-deoxyDHCer), this product is the N-acylated form of 1-deoxysphinganine, a potent inhibitor of sphingolipid metabolism. The biological activity of 1-deoxyDHCer is not clearly understood at this time.

N-C16-deoxysphinganine Commonly referred to as 1-deoxydihydroceramide (1-deoxyDHCer), is the N-acylated form of 1-deoxysphinganine, a potent inhibitor of sphingolipid metabolism. The N-acyl group can be 16, 20 and 24 carbon chain. N-acylsphinganines (dihydroceramides) are synthesized by the acylation of sphingoid bases in the presence of ceramide synthases (CerS).

생화학적/생리학적 작용

N-acylsphinganines (dihydroceramides) levels are lower during ceramide synthase inhibition. They are intermediates of ceramide and dihydrosphingolipids synthesis. Treatment of MCF7 cancer cells with fenretinide alters sphingolipid metabolism.

포장

5 mL Amber Glass Screw Cap Vial (860462P-1mg)

5 mL Amber Glass Screw Cap Vial (860462P-5mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3