860539P

C16 Glucosyl(β) Ceramide (d18:1/16:0)

Avanti Research^™ - A Croda Brand

• 동의어(들): D-glucosyl-β-1,1′-N-palmitoyl-D-erythro-sphingosine
• 실험식(Hill 표기법): C₄₀H₇₇NO₈
• CAS Number: 74365-77-8
• Molecular Weight: 700.04
• MDL number: MFCD22416657
• UNSPSC 코드: 12352211
• NACRES: NA.25

속성

• 양식: powder
• 포장: pkg of 1 × 25 mg (860539P-25mg); pkg of 1 × 5 mg (860539P-5mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand
• 지질 유형: sphingolipids
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: [H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O
• InChI key: VJLLLMIZEJJZTE-NNTBDIJYSA-N

설명

일반 설명

Glucosyl(β) Ceramide (β-GlcCer) is a naturally occurring glycolipid and an ubiquitous intracellular metabolite. It might be present in the endoplasmic reticulum or Golgi apparatus.

애플리케이션

C16 Glucosyl(β) Ceramide (d18:1/16:0) or D-glucosyl-β-1,1′-N-palmitoyl-D-erythro-sphingosine has been used as a stock solution for the in vitro treatment of bacteria and to study the role of sphingolipids on pulmonary Pseudomonas aeruginosa infections in cystic fibrosis (CF). It may be used in the quantification of lipid in green fluorescence protein (GFP) and fatty acid transport protein 4 (FATP4) cells using electrospray ionization tandem mass spectrometry (ESI-MS/MS).

생화학적/생리학적 작용

Glucosyl(β) Ceramide (β-GlcCer) is an endogenous macrophage inducible C-type lectin (Mincle) ligand, which has immunostimulatory property. It also stimulates inflammatory and acquired immune responses on myeloid cells through Mincle. It is a potential biomarker in Gaucher′s disease. β-GlcCer regulates the function of natural killer T (NKT) lymphocytes and exhibits antimetastatic effects. A balanced level of intracellular β-GlcCer is essential for maintaining tissue homeostasis.

포장

5 mL Amber Glass Screw Cap Vial (860539P-25mg)

5 mL Amber Glass Screw Cap Vial (860539P-5mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids