860576P

C16 Lactosyl(β) Ceramide (d18:1/16:0)

Avanti Research^™ - A Croda Brand 860576P, powder

• 동의어(들): D-lactosyl-β-1,1′ N-palmitoyl-D-erythro-sphingosine
• 실험식(Hill 표기법): C₄₆H₈₇NO₁₃
• CAS Number: 4201-62-1
• Molecular Weight: 862.18
• MDL number: MFCD08703001
• UNSPSC 코드: 12352211
• NACRES: NA.25

속성

• 양식: powder
• 포장: pkg of 1 × 5 mg (860576P-5mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand 860576P
• 지질 유형: sphingolipids
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: [H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O[C@H](O2)[C@H](O)[C@@H](O)[C@H]([C@H]2CO)O
• InChI: 1S/C46H87NO13/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-35(50)34(47-38(51)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)33-57-45-43(56)41(54)44(37(32-49)59-45)60-46-42(55)40(53)39(52)36(31-48)58-46/h27,29,34-37,39-46,48-50,52-56H,3-26,28,30-33H2,1-2H3,(H,47,51)
• InChI key: HLIJNIKSBCIDGO-QKLMXXKVSA-N

설명

일반 설명

Lactosylceramide (LacCer) is a glycosphingolipid, which is found majorly in the nervous system and myelin sheath. It comprises a hydrophobic ceramide lipid and a hydrophilic sugar moiety.

애플리케이션

C16 Lactosyl(β) Ceramide (d18:1/16:0) or D-lactosyl-β-1,1′ N-palmitoyl-D-erythro-sphingosine has been used as a lipid standard in mass spectrometry imaging of lipids in human skin disease model hidradenitis suppurativa. It may be used in the preparation of liposomes.

생화학적/생리학적 작용

Lactosylceramide (LacCer) is a structural and signaling lipid. It is crucial for signal transduction and cell adhesion. LacCer facilitates microbial attachment and also acts as an adhesion receptor for pathogens. It regulates cellular stress response and apoptosis. LacCer also modulates in cell proliferation and microbial pathogenesis. It is implicated in innate immune responses, host-tissue pathogen interactions and chronic inflammatory diseases.

포장

5 mL Amber Glass Screw Cap Vial (860576P-5mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids