모든 사진(3)
About This Item
Linear Formula:
NH2OH · HCl
CAS Number:
Molecular Weight:
69.49
Beilstein:
3539763
EC Number:
MDL number:
UNSPSC 코드:
12352300
PubChem Substance ID:
NACRES:
NA.21
추천 제품
vapor pressure
0.001 hPa ( 50 °C)
Quality Level
제품 라인
ReagentPlus®
분석
99%
양식
crystalline
기술
inhibition assay: suitable
pH
2.5-3.5 (20 °C, 50 g/L)
mp
155-157 °C (dec.) (lit.)
density
1.67 g/mL at 25 °C (lit.)
SMILES string
Cl.NO
InChI
1S/ClH.H3NO/c;1-2/h1H;2H,1H2
InChI key
WTDHULULXKLSOZ-UHFFFAOYSA-N
유사한 제품을 찾으십니까? 방문 제품 비교 안내
일반 설명
Hydroxylamine hydrochloride (Hydroxylammonium chloride) participates in the synthesis of 1,2,4-oxadiazoles, secondary amides and tertiary amides.
Hydroxylamine hydrochloride (NH2OH.HCl) is a hygroscopic salt widely used as a reactant in electrophilic substitution reactions, oxidation, and reduction reactions. It is also used in the synthesis of nitriles, pyrazoles, isoxazoles, nitrones, and pyridine.
애플리케이션
Hydroxylamine hydrochloride can be used as a reactant:
- in the synthesis of primary amides from aldehydes in the presence of cesium carbonate (Cs2CO3) as a catalyst.
- in the conversion of alicyclic /aliphatic carbonyl compounds and the aromatic aldehydes into corresponding oximes.
- in the one-pot synthesis of nitriles from aldehydes in the presence of sodium sulfate (anhyd) and sodium bicarbonate catalysts.
- It can also be used as a reducing agent in the preparation of single-layer reduced graphene oxide (RGO) sheets and films.
생화학적/생리학적 작용
MAO inhibitor; inhibits platelet aggregation.
법적 정보
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
신호어
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Carc. 2 - Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Oral
표적 기관
spleen
Storage Class Code
4.1A - Other explosive hazardous materials
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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Cell host & microbe, 28(5), 660-668 (2020-08-19)
Eradication of pathogens from the bloodstream is critical to prevent disseminated infections and sepsis. Kupffer cells in the liver form an intravascular firewall that captures and clears pathogens from the blood. Here, we show that the catching and killing of
Magnesia-supported hydroxylamine hydrochloride in the presence of sodium carbonate as an efficient reagent for the synthesis of 1, 2, 4-oxadiazoles from nitriles.
Kaboudin B and Saadati F.
Tetrahedron Letters, 48(16), 2829-2832 (2007)
Simbarashe Ngwerume et al.
The Journal of organic chemistry, 78(3), 920-934 (2012-12-29)
A novel gold-catalyzed method for the regioselective synthesis of highly substituted pyrroles directly from oximes and alkynes was developed via independent optimization of two key steps of the process. Importantly, a cationic gold(I) species was shown to activate multiple steps
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