17247

N-Dodecanoyl-DL-homoserine lactone

≥97.0% (HPLC), suitable for ligand binding assays

• 동의어(들): N-Lauroyl-DL-homoserine lactone
• 실험식(Hill 표기법): C₁₆H₂₉NO₃
• CAS Number: 18627-38-8
• Molecular Weight: 283.41
• MDL number: MFCD03100412
• UNSPSC 코드: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 57647620
• NACRES: NA.26

속성

• Product Name: N-Dodecanoyl-DL-homoserine lactone, ≥97.0% (HPLC)
• Quality Level: 100
• 분석: ≥97.0% (HPLC)
• 양식: powder
• 기술: ligand binding assay: suitable
• 색상: white to faint beige
• mp: 114-117 °C
• 저장 온도: 2-8°C
• SMILES string: CCCCCCCCCCCC(=O)NC1CCOC1=O
• InChI: 1S/C16H29NO3/c1-2-3-4-5-6-7-8-9-10-11-15(18)17-14-12-13-20-16(14)19/h14H,2-13H2,1H3,(H,17,18)
• InChI key: WILLZMOKUUPJSL-UHFFFAOYSA-N

설명

애플리케이션

Application test: Induces violacein expression in a Chromobacterium violaceum mutant usually not able to produce homoserine lactones.

생화학적/생리학적 작용

N-Dodecanoyl-DL-homoserine lactone (C12-HSL) is among a group of homoserine lactones that includes; N-Heptanoyl-DL-homoserine lactone (C7HSL), N-octanoyl-homoserine lactone (N-C8-HSL), N-Decanoyl-DL-homoserine lactone (N-C10-HSL), N-(3-oxodecanoyl) homoserine-L-lactone (3-oxo-C10 HSL), N-(3-oxododecanoyl)homoserine-L-lactone (3-oxo-C12-HSL), N-(3-Oxotetradecanoyl)-L-homoserine lactone (3-oxo-C14-HSL, N-(3-hydroxydecanoyl)-L-homoserine lactone, and N-(3-hydroxyoctanoyl)-L-homoserine lactone involved in the processes of bacterial quorum sensing. These N-acyl-homoserine lactones are used to study the processes and mechanisms of bacterial quorum sensing.

N-Lauroyl- DL-homoserine lactone is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) regulate gene expression in gram-negative bacteria, such as Echerichia and Salmonella are involved in quorum sensing, cell to cell communication among bacteria. Some AHLs are potent chemoattractants for human immune cells such as neutrophils.

Quorum-sensing signal generation.

포장

Bottomless glass bottle. Contents are inside inserted fused cone.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)