모든 사진(1)
About This Item
실험식(Hill 표기법):
C26H24N2O4
CAS Number:
Molecular Weight:
428.48
MDL number:
UNSPSC 코드:
12352204
NACRES:
NA.77
추천 제품
생물학적 소스
synthetic (organic)
Quality Level
분석
>95% (HPLC)
양식
powder
분자량
Mw 428.5
solubility
DMSO: 10 mg/mL, clear, colorless to greenish-yellow
저장 온도
−20°C
SMILES string
N(c2ccc(cc2)c3ccc(cc3)C(=O)[C@H]4[C@@H](CCC4)C(=O)O)C(=O)Nc1ccccc1
InChI
1S/C26H24N2O4/c29-24(22-7-4-8-23(22)25(30)31)19-11-9-17(10-12-19)18-13-15-21(16-14-18)28-26(32)27-20-5-2-1-3-6-20/h1-3,5-6,9-16,22-23H,4,7-8H2,(H,30,31)(H2,27,28,32)/t22-,23-/m1/s1
InChI key
BOZRFEQDOFSZBV-DHIUTWEWSA-N
관련 카테고리
애플리케이션
A922500 has been used in the inhibition of diacylglycerol acyltransferase (DGAT) in epithelial human breast cancer cell line (MDA-MB-231), digitonin-permeabilized human cancer cells, human myotubes and macrophages.
생화학적/생리학적 작용
Diacylglycerol acyltransferase (DGAT-1) inhibitor; IC50 7 to 24 nM
The diacylglycerol acyltransferase (DGAT) 1 inhibitor A922500 was shown to effectively reduce postprandial serum triglyceride levels in rodents at concentrations of 0.03, 0.3 and 3 mg/kg. These results suggest A922500 may have beneficial effects in reducing the risk of cardiovascular disease.
물리적 형태
A922500 is supplied as a crystalline solid.
제조 메모
A stock solution may be made by dissolving the A922500 in the solvent of choice. A922500 is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide (DMF).
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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