A231

Arachidonyl trifluoromethyl ketone

oil, ≥97% (NMR)

• 동의어(들): 1,1,1-Trifluoromethyl-6,9,12,15-heieicosatetraen-2-one, AACOCF₃, Arach-CF₃
• 실험식(Hill 표기법): C₂₁H₃₁F₃O
• CAS Number: 149301-79-1
• Molecular Weight: 356.47
• MDL number: MFCD00236427
• UNSPSC 코드: 51111800
• PubChem Substance ID: 24890647
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥97% (NMR)
• 양식: oil
• 저장 조건: desiccated; protect from light; under inert gas
• 색상: yellow
• solubility: DMSO: >5 mg/mL
• 저장 온도: −20°C
• SMILES string: CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)C(F)(F)F
• InChI: 1S/C21H31F3O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(25)21(22,23)24/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3/b7-6-,10-9-,13-12-,16-15-
• InChI key: PLWROONZUDKYKG-DOFZRALJSA-N
• 유전자 정보: human ... PLA2G1B(5319)

설명

애플리케이션

Arachidonyl trifluoromethyl ketone (AACOCF3) has been used as a anandamide degradation inhibitor to study its effects in primary astrocyte cultures.

생화학적/생리학적 작용

Arachidonyl trifluoromethyl ketone (AACOCF3) plays a role in the inhibition of 12-hydroxyeicosatetraenoic acid (12-HETE) and thromboxane B2 produced by the platelets.

Inhibits anandamide hydrolysis in vitro; inhibits phospholipase A₂.

특징 및 장점

This compound is featured on the Phospholipase A2 page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

주의사항

Hygroscopic, photosensitive, air sensitive

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)