A4660

6-Thioguanine

Hybri-Max^™, 50 ×, γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma

• 동의어(들): 2-Amino-6-mercaptopurine, 2-Amino-6-purinethiol
• 실험식(Hill 표기법): C₅H₅N₅S
• CAS Number: 154-42-7
• Molecular Weight: 167.19
• Beilstein: 157765
• EC Number: 205-827-2
• MDL number: MFCD00233553
• UNSPSC 코드: 12352207
• PubChem Substance ID: 24890892
• NACRES: NA.75

속성

• 생물학적 소스: synthetic (organic)
• Quality Level: 200
• Grade: Hybri-Max^™
• 무균: γ-irradiated
• 제품 라인: BioXtra
• 분석: ~98%
• 양식: lyophilized powder
• 농도: 50 ×
• 기술: cell culture | hybridoma: suitable
• 불순물: endotoxin, tested
• mp: ≥300 °C (lit.)
• solubility: 1 M NaOH: 50 mg/mL, clear to slightly hazy
• 저장 온도: room temp
• SMILES string: NC1=Nc2nc[nH]c2C(=S)N1
• InChI: 1S/C5H5N5S/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)
• InChI key: WYWHKKSPHMUBEB-UHFFFAOYSA-N
• 유전자 정보: human ... IMPDH1(3614), IMPDH2(3615)

설명

애플리케이션

Used in hybridoma formation applications as a selection agent.

생화학적/생리학적 작용

Ribosylated and phosphorylated by the same pathway as natural purine bases; as the nucleotide, inhibits a variety of cellular processes involved in nucleic acid synthesis. Has a long history as an effective treatment of leukemia.

재구성

Reconstitute contents of vial with 10 ml sterile cell culture medium. Stock solution is sufficient to prepare 500 ml medium. Final working concentration: 30 μM 2-amino-6-mercaptopurine.

법적 정보

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301
• 예방조치 성명서: P301 + P310
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges