852678

6-Mercaptopurine monohydrate

98%

• 동의어(들): 6-Purinethiol, 6-Thiohypoxanthine
• 실험식(Hill 표기법): C₅H₄N₄S · H₂O
• CAS Number: 6112-76-1
• Molecular Weight: 170.19
• Beilstein: 4012091
• EC Number: 200-037-4
• MDL number: MFCD03854445
• UNSPSC 코드: 12352005
• PubChem Substance ID: 24888330
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: 98%
• 양식: powder
• mp: >300 °C (lit.)
• SMILES string: O.Sc1ncnc2[nH]cnc12
• InChI: 1S/C5H4N4S.H2O/c10-5-3-4(7-1-6-3)8-2-9-5;/h1-2H,(H2,6,7,8,9,10);1H2
• InChI key: WFFQYWAAEWLHJC-UHFFFAOYSA-N
• 유전자 정보: human ... PPAT(5471)

설명

일반 설명

6-Mercaptopurine monohydrate is an antimetabolite and antineoplastic drug. Its cocrystallization with 4-hydroxybenzoic acid and 2,4-dihydroxybenzoic acid or salt formation with piperazine may improve its aqueous solubility.

애플리케이션

6-Mercaptopurine is a widely used antileukemic agent that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA.

안전성 정보

• 픽토그램: GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H301,H341,H361fd
• 예방조치 성명서: P202 - P264 - P280 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral - Muta. 2 - Repr. 2
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves