A9135

Ethyl arachidonate

≥98.5% (GC), liquid

• 동의어(들): 5,8,11,14-Eicosatetraenoic acid ethyl ester, Arachidonic acid ethyl ester
• 실험식(Hill 표기법): C₂₂H₃₆O₂
• CAS Number: 1808-26-0
• Molecular Weight: 332.52
• MDL number: MFCD00038340
• UNSPSC 코드: 12352211
• PubChem Substance ID: 24891398
• NACRES: NA.25

속성

• 생물학적 소스: fungus
• Quality Level: 100
• 분석: ≥98.5% (GC)
• 양식: liquid
• 작용기: ester
• 지질 유형: omega FAs
• 배송 상태: ambient
• 저장 온도: −20°C
• SMILES string: CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCC
• InChI: 1S/C22H36O2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24-4-2/h8-9,11-12,14-15,17-18H,3-7,10,13,16,19-21H2,1-2H3/b9-8-,12-11-,15-14-,18-17-
• InChI key: SNXPWYFWAZVIAU-GKFVBPDJSA-N

설명

생화학적/생리학적 작용

Arachidonic acid (AA) is an unsaturated omega-6 fatty acid constituent of the phospholipids of cell membranes. Phospholipase A2 releases AA from the membrane phospholipids in response to inflammation. AA is subsequently metabolized to prostaglandins and thromboxanes by at least two cyclooxygenase (COX) isoforms, to leukotrienes and lipoxins by lipoxygenases, and to epoxyeicosatrienoic acids via p450-catalyzed metabolism. AA and its metabolites play important roles in a variety of biological processes, including signal transduction, contraction, chemotaxis, and cell proliferation, differentiation and apoptosis. AA has been demonstrated to bind to the α subunit of G protein and inhibit the activity of Ras GTPase-activating proteins (GAPs). Cellular uptake of AA is energy dependent and involves protein-facilitated transport across the plasma membrane.

포장

Sealed ampule.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves