B2929

B-Lymphocyte Chemoattractant human

≥95% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

• 동의어(들): B-Cell Attracting Chemokine 1, BCA-1, BLC
• MDL number: MFCD01867020
• UNSPSC 코드: 12352202
• NACRES: NA.32

속성

• 생물학적 소스: human
• Quality Level: 200
• 재조합: expressed in E. coli
• 분석: ≥95% (SDS-PAGE)
• 양식: lyophilized powder
• 효능: 0.1000 μg/mL
• 분자량: apparent mol wt 8.7 kDa by SDS-PAGE (reducing)
• 포장: pkg of 25 μg
• 저장 조건: avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)
• 기술: cell culture | mammalian: suitable
• 불순물: endotoxin, tested
• UniProt 수납 번호: O43927
• 저장 온도: −20°C
• 유전자 정보: human ... CXCL13(10563)

설명

생화학적/생리학적 작용

BCA-1 is a potent chemoattractant for B lymphocytes, but not T lymphocytes, monocytes, or neutrophils.

BCA-1 is a potent chemoattractant for B lymphocytes, but not T lymphocytes, monocytes, or neutrophils. Its specific receptor BLR1 is a G protein-coupled receptor originally isolated from Burkitt′s lymphoma cells. Among cells of the hematopoietic lineages, the expression of BRL1, now designated CXCR5, is restricted to B lymphocytes and a subpopulation of T helper memory cells.

Potent chemoattractant for B lymphocytes, but not T lymphocytes, monocytes, or neutrophils.

The biological activity of human BLC/BCA-1 is measured by its ability to chemoattract mouse BaF/3 cells transfected with human CXCR5.

물리적 형태

Lyophilized from a 0.2 μm filtered solution in 35% acetonitrile and 0.1% TFA containing 50 μg bovine serum albumin per 1 μg of cytokine.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302 + H332,H319
• 예방조치 성명서: P261 - P264 - P270 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable