B5050

Monoclonal Anti-Brain-derived Neurotrophic Factor antibody produced in mouse

clone 35928.11, purified immunoglobulin, lyophilized powder

• 동의어(들): Anti-BDNF
• MDL number: MFCD01633045
• UNSPSC 코드: 51111800
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 35928.11, monoclonal
• 양식: lyophilized powder
• 종 반응성: human
• 기술: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 8-25 μg/mL using human spinal cord; western blot: 1-2 μg/mL
• 동형: IgG1
• UniProt 수납 번호: P23560
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... BDNF(627)

설명

일반 설명

The antibody shows ~5% cross-reactivity with recombinant human β−NGF and recombinant rat β−NGF.

면역원

Recombinant human BDNF, expressed in Sf 21 cells.

애플리케이션

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)

생화학적/생리학적 작용

Brain derived neurotrophic factor (BDNF) belongs to a family of secreted proteins called neurotrophins that includes, nerve growth factor (NGF), neurotrophin-3 (NT3) and NT4/5. BDNF is expressed in the developing and the mature brain. The downstream pathways promoted by BDNF include PI3K, MAPK and JAK/STAT. The most important role of BDNF is the regulation of synaptic transmission and plasticity, protein synthesis and phosphorylation of local proteins.

물리적 형태

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

제조 메모

Purified from ascites fluid using protein A.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable