B9561

Monoclonal Anti-Brain-derived Neurotrophic Factor antibody produced in mouse

clone 35909, purified immunoglobulin, lyophilized powder

• 동의어(들): Anti-BDNF
• MDL number: MFCD01633045
• UNSPSC 코드: 51111800
• NACRES: NA.43

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 35909, monoclonal
• 양식: lyophilized powder
• 종 반응성: human
• 기술: flow cytometry: 25 μg/mL
• 동형: IgG1
• UniProt 수납 번호: P23560
• 저장 온도: −20°C
• 유전자 정보: human ... BDNF(627)

설명

일반 설명

Brain derived neurotrophic factor (BDNF) belongs to a family of secreted proteins called neurotrophins that includes, nerve growth factor (NGF), neurotrophin-3 (NT3) and NT4/5. BDNF is expressed in the developing and the mature brain. The influence of BDNF is mediated by its binding to TrkB receptor and sometimes the receptor p75^NTR. The downstream pathways promoted by BDNF include PI3K, MAPK and JAK/STAT. The most important role of BDNF is the regulation of synaptic transmission and plasticity, protein synthesis and phosphorylation of local proteins. The secretion of BDNF is highly regulated at both transcriptional and translational levels since it is involved in the proper function of neuronal circuit and development of cognitive functions. The deficits in BDNF functions are implicated in a number of neurodegenerative disorders such as Huntington′s disease, schizophrenia and dementia
Monoclonal Anti-Brain-derived Neurotrophic Factor detects human BDNF.

면역원

purified, Sf21-derived recombinant human brain-derived neurotrophic factor.

애플리케이션

Monoclonal Anti-Brain-derived Neurotrophic Factor may be used to detect human BDNF by flow cytometry using a working antibody concentration of 25 μg/ml.

물리적 형태

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)