B5435

BIA 2-093

≥98% (HPLC), solid

• 동의어(들): S-(−)-10-Acetoxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide
• 실험식(Hill 표기법): C₁₇H₁₆N₂O₃
• CAS Number: 236395-14-5
• Molecular Weight: 296.32
• MDL number: MFCD06798333
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24891837
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: solid
• 색상: white
• solubility: DMSO: ~21 mg/mL; H₂O: insoluble
• 저장 온도: 2-8°C
• SMILES string: CC(=O)O[C@H]1Cc2ccccc2N(C(N)=O)c3ccccc13
• InChI: 1S/C17H16N2O3/c1-11(20)22-16-10-12-6-2-4-8-14(12)19(17(18)21)15-9-5-3-7-13(15)16/h2-9,16H,10H2,1H3,(H2,18,21)/t16-/m0/s1
• InChI key: QIALRBLEEWJACW-INIZCTEOSA-N
• 유전자 정보: human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335) ; rat ... Scnn1g(24768)

설명

생화학적/생리학적 작용

Blocker of voltage-gated sodium channels; significantly blocks excitatory amino acid (glutamate and aspartate) release.

Blocks voltage-gated sodium channels and excitatory amino acid release.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves