C5134

2-Chloroadenosine

• 동의어(들): 2-CADO, 6-Amino-2-chloropurine riboside
• 실험식(Hill 표기법): C₁₀H₁₂ClN₅O₄
• CAS Number: 146-77-0
• Molecular Weight: 301.69
• Beilstein: 43957
• EC Number: 205-678-3
• MDL number: MFCD00005734
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24277688
• NACRES: NA.77

속성

• 양식: powder
• Quality Level: 200
• SMILES string: Nc1nc(Cl)nc2n(cnc12)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O
• InChI: 1S/C10H12ClN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6-,9-/m1/s1
• InChI key: BIXYYZIIJIXVFW-UUOKFMHZSA-N
• 유전자 정보: human ... ADORA1(134), ADORA3(140) ; rat ... Adora1(29290), Adora2a(25369), Adora3(25370)

설명

애플리케이션

2-Chloroadenosine has been used:

• as an agonist of adenosine receptors (A1R) in dorsal hippocampus (DH) and ventral hippocampus (VH) of mice
• as a component of artificial cerebrospinal fluid (aCSF) for electrophysiological experiments using hippocampal slices
• as an internal standard in solid phase extraction coupled with liquid chromatography-tandem mass spectrometry (XLC-MS/MS) for the quantification of certain metabolites from axonal lysates and dorsal root ganglia (DRG) neurons

생화학적/생리학적 작용

2-Chloroadenosine is an analog of adenosine. It is an adenosine A1 receptor agonist. It might possess anti-oxidant property.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)