C7397

Cyclophosphamide monohydrate

ISOPAC^®

• 동의어(들): 2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide, Cytoxan
• 실험식(Hill 표기법): C₇H₁₅Cl₂N₂O₂P · H₂O
• CAS Number: 6055-19-2
• Molecular Weight: 279.10
• Beilstein: 4678992
• EC Number: 200-015-4
• MDL number: MFCD00149395
• UNSPSC 코드: 51112507
• PubChem Substance ID: 24892961
• NACRES: NA.25

속성

• 분석: 97.0-103.0% (HPLC)
• 양식: powder
• mp: 49-51 °C (lit.)
• 저장 온도: 2-8°C
• SMILES string: [H]O[H].ClCCN(CCCl)P1(=O)NCCCO1
• InChI: 1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2
• InChI key: PWOQRKCAHTVFLB-UHFFFAOYSA-N

설명

애플리케이션

Cyclophosphamide, a nitrogen mustard DNA alkylating agent, is used to study its mechanisms of action as an anticancer and antiimmunity drug.

생화학적/생리학적 작용

Cyclophosphamide is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.

Cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations.

포장

Packaged in a 100 mL serum bottle with silicon/PTFE septum and aluminum tear seal.

주의사항

Injecting a compatible solvent directly into the vial permits preparation of any desired strength solution without exposure.

재구성

Dissolving the contents in 100 mL of solvent yields a 1% solution.

법적 정보

Isopac is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H301,H340,H350,H360FD
• 예방조치 성명서: P202 - P264 - P280 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral - Carc. 1B - Muta. 1B - Repr. 1A
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges