E2031

Eliprodil

≥98% (HPLC), powder

• 동의어(들): α-(4-Chlorophenyl)-4-[(4-fluorophenyl)methyl]-1-piperidineethanol, SL 820715
• 실험식(Hill 표기법): C₂₀H₂₃ClFNO
• CAS Number: 119431-25-3
• Molecular Weight: 347.85
• MDL number: MFCD00866651
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24277709
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 5 mg/mL, clear; H₂O: insoluble
• 주관자: Sanofi Aventis
• 저장 온도: 2-8°C
• SMILES string: OC(CN1CCC(CC1)Cc2ccc(F)cc2)c3ccc(Cl)cc3
• InChI: 1S/C20H23ClFNO/c21-18-5-3-17(4-6-18)20(24)14-23-11-9-16(10-12-23)13-15-1-7-19(22)8-2-15/h1-8,16,20,24H,9-14H2
• InChI key: GGUSQTSTQSHJAH-UHFFFAOYSA-N
• 유전자 정보: human ... GRIN2B(2904) ; rat ... Adra1a(29412)

설명

생화학적/생리학적 작용

NR2B selective NMDA glutamate receptor antagonist which appears to target the "polyamine site" on the NMDA receptor, setting it apart from other NR2B receptor antagonists. Possesses neuroprotective effects in models of ischemia, but prolongs the QT interval in patients; currently under investigation for acute and chronic pain.

NR2B selective NMDA glutamate receptor antagonist.

특징 및 장점

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves