E3263

Efaroxan hydrochloride

≥98% (HPLC)

• 동의어(들): 2-Ethyl-2-(imidazolin-2-yl)-2,3-dihydrobenzofuran hydrochloride, RX 821037A
• 실험식(Hill 표기법): C₁₃H₁₆N₂O · HCl
• CAS Number: 89197-00-2
• Molecular Weight: 252.74
• MDL number: MFCD00069270
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24278415
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• solubility: H₂O: >20 mg/mL
• SMILES string: Cl.CCC1(Cc2ccccc2O1)C3=NCCN3
• InChI: 1S/C13H16N2O.ClH/c1-2-13(12-14-7-8-15-12)9-10-5-3-4-6-11(10)16-13;/h3-6H,2,7-9H2,1H3,(H,14,15);1H
• InChI key: DWOIUCRHVWIHAH-UHFFFAOYSA-N
• 유전자 정보: human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152)

설명

생화학적/생리학적 작용

(+)-Isomer is a selective α-adrenoceptor antagonist; (−)-isomer is an imidazoline ligand that induces insulin secretion, mediated by the blockade of ATP-sensitive potassium channels in pancreatic β cells; I₁ imidazoline binding site antagonist.

(+)-Isomer is a selective α-adrenoceptor antagonist; (−)-isomer is an imidazoline ligand; I₁ imidazoline binding site antagonist.

특징 및 장점

This compound is featured on the Imidazoline Binding Sites and Potassium Channels pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301
• 예방조치 성명서: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges