E8280

Exo 1

≥98% (HPLC), solid

• 동의어(들): 2-(4-Fluorobenzoylamino)benzoic acid methyl ester, 2-(4-Fluorobenzoylamino)methylbenzoate
• 실험식(Hill 표기법): C₁₅H₁₂NFO₃
• CAS Number: 75541-83-2
• Molecular Weight: 273.26
• MDL number: MFCD00028104
• UNSPSC 코드: 12352203
• PubChem Substance ID: 24724477
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: solid
• solubility: DMSO: soluble 19 mg/mL
• SMILES string: COC(=O)c1ccccc1NC(=O)c2ccc(F)cc2
• InChI: 1S/C15H12FNO3/c1-20-15(19)12-4-2-3-5-13(12)17-14(18)10-6-8-11(16)9-7-10/h2-9H,1H3,(H,17,18)
• InChI key: KIAPWMKFHIKQOZ-UHFFFAOYSA-N

설명

애플리케이션

Exo 1 has been used as a component of the BRB80 buffer to study coat protein 1 (COPI)-mediated membrane trafficking. It has also been used as a Golgi inhibitor to study its effects on the long interspersed nuclear element-1 (L1) retrotransposition.

생화학적/생리학적 작용

Exo 1 is a cell-permeable methylanthranilate analog that promotes the release of adenosine diphosphate (ADP)-ribosylation factor (ARF) 1 from Golgi membranes. It also inhibits the membrane trafficking between the endoplasmic reticulum (ER) and the Golgi bodies.

Reversible inhibitor of exocytosis; Golgi ARF 1 (ADP-Ribosylation Factor) GTPase activator.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)