F5130

5-Fluorouridine

proapoptotic anitproliferative plant growth regulator

• 동의어(들): 5-Fluorouracil 1β-D-ribofuranoside, FUrd
• 실험식(Hill 표기법): C₉H₁₁FN₂O₆
• CAS Number: 316-46-1
• Molecular Weight: 262.19
• Beilstein: 33662
• EC Number: 206-260-3
• MDL number: MFCD00036832
• UNSPSC 코드: 41106305
• PubChem Substance ID: 24894883
• NACRES: NA.51

속성

• 생물학적 소스: synthetic (organic)
• Quality Level: 100
• 분석: ≥99% (HPLC)
• 양식: powder
• solubility: water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
• SMILES string: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=C(F)C(=O)NC2=O
• InChI: 1S/C9H11FN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1
• InChI key: FHIDNBAQOFJWCA-UAKXSSHOSA-N

설명

일반 설명

5-Fluorouridine (FUrd) is a fluoropyrimidine nucleoside analog and a cell-permeable modified RNA precursor.

애플리케이션

5-Fluorouridine has been used for labeling active transcription sites in the porcine fetal fibroblasts and human cell lines for immunocytochemistry analysis. It has also been used to monitor apoptosis during drug sensitivity assay in esophageal squamous cell carcinoma (ESCC) cells.

생화학적/생리학적 작용

5-Fluorouridine (FUrd) is cytotoxic towards cancer cells. FUrd is often used in chemical and biochemical comparison studies with fluorouracil and thymine analogs.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves