F5251

p-Fluoro-DL-phenylalanine

≥98.0% (TLC)

• 동의어(들): 4-fluoro-phenylalanine
• Linear Formula: FC₆H₄CH₂CH(NH₂)COOH
• CAS Number: 51-65-0
• Molecular Weight: 183.18
• Beilstein: 2938793
• EC Number: 200-113-7
• MDL number: MFCD00002600
• UNSPSC 코드: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24894885
• NACRES: NA.26

속성

• Product Name: p-Fluoro-DL-phenylalanine,
• 분석: ≥98.0% (TLC)
• Quality Level: 100
• 양식: powder
• 색상: white to off-white
• mp: 253-255 °C (dec.) (lit.)
• 응용 분야: peptide synthesis
• SMILES string: NC(Cc1ccc(F)cc1)C(O)=O
• InChI: 1S/C9H10FNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)
• InChI key: XWHHYOYVRVGJJY-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

Inhibits mitosis and reversibly arrests HeLa cells in G2.

p-Fluoro-DL-phenylalanine (pFPhe), a toxic antimetabolite, is a racemic mixture of a substituted (halogenated) benzoyl D and L phenylalanine useful as a selection marker for wine yeast transformation and with potential use in endomorphin, antiviral, and antimicrobial drug development. Phenylalanine analogue, rho-fluorophenylalanine (pFPhe) is also used to induce apoptosis.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H300
• 예방조치 성명서: P264 - P301 + P310
• Hazard Classifications: Acute Tox. 2 Oral
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges