G1001

D-Glutamic acid

≥99% (TLC), suitable for ligand binding assays

• 동의어(들): (R)-2-Aminoglutaric acid, (R)-2-Aminopentanedioic acid, D-Glu, R-(−)-1-Aminopropane-1,3-dicarboxylic acid
• Linear Formula: HO₂CCH₂CH₂CH(NH₂)CO₂H
• CAS Number: 6893-26-1
• Molecular Weight: 147.13
• Beilstein: 1723800
• EC Number: 230-000-8
• MDL number: MFCD00063112
• UNSPSC 코드: 12352209
• PubChem Substance ID: 24895031
• NACRES: NA.32

속성

• Product Name: D-Glutamic acid, ≥99% (TLC)
• Quality Level: 200
• 분석: ≥99% (TLC)
• 양식: powder
• 기술: ligand binding assay: suitable
• 색상: white to off-white
• mp: 200-202 °C (subl.) (lit.)
• SMILES string: N[C@H](CCC(O)=O)C(O)=O
• InChI: 1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1
• InChI key: WHUUTDBJXJRKMK-GSVOUGTGSA-N
• 유전자 정보: human ... CCR2(1231)

설명

일반 설명

D-Glutamic acid is an essential constituent of the bacterial peptidoglycan structure. It is added to UDP-N-acetylmuramyl-L-alanine (UDP-MurNAc-L-alanine) by the enzyme D-glutamic acid-adding enzyme (murD). This is, then, incorporated into the peptidoglycan precursor. Peptidoglycan makes up the cell walls of Gram-positive and -negative bacteria. The conversion of L-glutamate to D-glutamate by glutamate racemase (GR) enzyme is an essential step in the synthesis of peptidoglycan.

애플리케이션

D-glutamic acid is suitable for use in the structure-affinity relationship (SAR)-study of GR (glutamate racemase) enzyme and its inhibitors.

생화학적/생리학적 작용

Unnatural isomer of glutamic acid.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)