G9270

γ-Glutamyltranspeptidase from equine kidney

Type VI, 5-12 units/mg solid

• 동의어(들): γ-GT, γ-Glutamyltransferase, (5-Glutamyl)peptide:amino-acid 5-glutamyltransferase, GGTP
• CAS Number: 9046-27-9
• EC 번호: 2.3.2.2 (BRENDA, IUBMB)
• EC Number: 232-931-5
• MDL number: MFCD00131126
• UNSPSC 코드: 12352204
• NACRES: NA.54

속성

• 생물학적 소스: equine kidney
• Quality Level: 200
• 유형: Type VI
• 양식: solid
• 특이 활성도: 5-12 units/mg solid
• 저장 온도: −20°C

설명

일반 설명

Gamma-Glutamyltranspeptidase is a heterodimeric enzyme and belongs to the superfamily of N-terminal nucleophile hydrolases.

애플리케이션

Gamma-glutamyltranspeptidase from equine kidney has been used:

• to identify the formation of 4-S-Cysteinyltetrodotoxin in the liver of Fugu pardalis
• as a standard to determine the activity of gamma-glutamyltransferase from human B-cell lymphoma cell lysates
• to hydrolyze isopeptides to study its effects on tubulin aggregation

생화학적/생리학적 작용

Gamma-Glutamyltranspeptidase participates in glutathione metabolism and it catalyzes the cleavage of gamma-glutamyl compounds, such as glutathione. It also plays a role in the transfer of gamma-glutamyl moiety to amino acids and peptides.

품질

Crude

단위 정의

One unit will liberate 1.0 μmole of p-nitroaniline from L-γ-glutamyl-p-nitroanilide per min at pH 8.5 at 25°C.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)