H1038

Hck human

recombinant, expressed in E. coli BL21, vial of ≥200 units

• MDL number: MFCD03792313
• UNSPSC 코드: 12352204
• NACRES: NA.54

속성

• 재조합: expressed in E. coli BL21
• Quality Level: 200
• 양식: solution
• 특이 활성도: 1-2 unit/μg protein
• 포장: vial of ≥200 units
• 관련 질환(들): cancer (leukemia)
• 배송 상태: dry ice
• 저장 온도: −70°C

설명

애플리케이션

Hck is a protein-tyrosine kinase that is expressed in hemopoietic cells. It is used in leukemia research .

생화학적/생리학적 작용

Hck is a member of the Src tyrosine kinase family. Hck has been shown to associate with and be activated by Bcr-Abl, which is a protein-tyrosine kinase that is expressed in chronic myelogenous leukemia .

단위 정의

One unit will phosphorylate 1.0 picomole of Tyr¹⁵ of the peptide substrate p^{cdc2 6-20} per minute at 30 °C at pH 7.4.

물리적 형태

Supplied as a solution in 50 mM Tris HCl, pH 7.4, 1 mM EDTA and 1 mM DTT

안전성 정보

• Storage Class Code: 10 - Combustible liquids