I1020

IL-4 mouse

≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

• 동의어(들): Interleukin-4, mIL-4, Interleukin-4 human
• MDL number: MFCD00166698
• UNSPSC 코드: 12352202
• NACRES: NA.77

속성

• 제품명: Interleukin-4 from mouse, IL-4, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
• 생물학적 소스: mouse
• 재조합: expressed in E. coli
• 분석: ≥98% (SDS-PAGE)
• 양식: lyophilized powder
• 효능: 0.1-2.0 ng/mL ED₅₀/EC₅₀
• 품질: endotoxin tested
• 분자량: ~13.5 kDa
• 포장: pkg of 5 μg
• 기술: cell culture | mammalian: suitable
• 불순물: <0.1 EU/μg
• UniProt 수납 번호: P07750
• 저장 온도: −20°C
• 유전자 정보: mouse ... Il4(16189)

설명

애플리케이션

Interleukin-4 from mouse has been used:

• as a component of cell culture media for class switch recombination assay
• to study its therapeutic benefits for mucosal healing
• as a pioglitazone or new peroxisome proliferator-activated receptor agonist (GQ-11)

생화학적/생리학적 작용

Interleukin-4 (IL-4) is a lymphokine with profound effects on the growth and differentiation of immunologically competent cells. IL-4 is also known as B cell stimulatory factor-1 (BSF-1), T cell growth factor-2 (TCGF-2) and mast-cell growth factor-2 (MCGF-2). Inhibits VEGF-induced and FGF-Basic-induced angiogenesis. IL-4 is a complex glycoprotein released by a subset of activated T cells. Treatment of IL-4 with specific glycosidases yields an active polypeptide. Human and mouse IL-4 share 50% amino acid sequence homology, but their biological actions are species-specific.

Interleukin-4, a lymphokine with profound effects on the growth and differentiation of immunologically competent cells, inhibits VEGF-induced and bFGF-induced angiogenesis. Human and mouse IL-4 share 50% amino acid sequence identity, but their biological actions are species-specific.

물리적 형태

Lyophilized, 0.2 μm filtered, with no additives.

분석 메모

The proliferative activity is tested in culture using mouse HT-2 cells.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)