I5659

Idebenone

≥98% (HPLC), powder

• 동의어(들): 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
• 실험식(Hill 표기법): C₁₉H₃₀O₅
• CAS Number: 58186-27-9
• Molecular Weight: 338.44
• MDL number: MFCD00274552
• UNSPSC 코드: 12352204
• PubChem Substance ID: 329815386
• NACRES: NA.25

속성

• Product Name: Idebenone, ≥98% (HPLC)
• Quality Level: 200
• 분석: ≥98% (HPLC)
• 양식: powder
• solubility: methanol: 50 mg/mL, clear to slightly hazy
• 저장 온도: room temp
• SMILES string: O=C(C(OC)=C1OC)C(CCCCCCCCCCO)=C(C)C1=O
• InChI: 1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3
• InChI key: JGPMMRGNQUBGND-UHFFFAOYSA-N

설명

일반 설명

Idebenone is a short-chain benzoquinone drug.

애플리케이션

Idebenone has been used:

• to treat mutant myocilin (mMYOC) cells for drug treatment assay
• to validate C2C12 secondary cell screening assay
• to treat obese mice, to test whether idebenone and CoQ10 bind directly to peroxisome proliferator-activated receptor (PPAR)LBDs, His-tagged PPARα, δ and γ LBDs

생화학적/생리학적 작용

A short-chain Coenzyme Q analog that enhances superoxide formation, presumably by mediating electron transfer from N2 to oxygen.

Idebenone is used in the treatment of visual impairment in adolescents and adults with Leber′s hereditary optic neuropathy (LHON). It serves as an antioxidant. It helps to guard the heart muscle against oxidative stress.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable